Web28. feb 2024 · Abstract. The present study demonstrates how TOP3B is involved in suppressing R-loops. Elevated R-loops were observed in TOP3B knockout cells (TOP3BKO) and suppressed by TOP3B transfection.Additionally, R-loop-inducing agents, the topoisomerase I inhibitor camptothecin, and the splicing inhibitor pladienolide-B, also … WebThe gene product of TOP3B, TOP3b, was recently shown to interact with FMRP, the protein deficient in Fragile X syndrome, a syndromic form of autism, and that this interaction was …
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WebAnti-TOP3B Antibody detects endogenous levels of total TOP3B protein. Immunogen The antiserum was produced against synthesized peptide derived from human TOP3B. convert ms/cm to salinity
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WebThe Topoisomerase 3B (Top3b) - Tudor domain containing 3 (Tdrd3) protein complex is the only dual-activity topoisomerase complex in animals that can alter the topology of both DNA and RNA. TOP3B mutations in humans are associated with schizophrenia, autism and cognitive disorders; and Top3b -null mice exhibit several phenotypes observed in ... WebAnti-Topo IIIβ-1 Antibody (B-10) is a mouse monoclonal IgG 2b κ Topo IIIβ-1 antibody, cited in 1 publications, provided at 200 µg/ml. raised against amino acids 563-862 of Topo IIIβ … WebRetired husband syndrome (主人 在 宅ストレス症候群, Shujin Zaitaku Sutoresu Shoukougun, literally "One's Husband Being at Home Stress Syndrome")[1] (RHS) is a psychosomatic stress-related illness which has been estimated to occur in 60% of Japan's older female population.[2] It is a condition where a woman begins to exhibit signs of physical illness … convert ms contin to fentanyl