WebAug 31, 2024 · Abstract and Figures. We retrospectively examined the nonclinical studies conducted with 17 CD3 bispecific constructs in support of first-in-human (FIH) trials in oncology. We also collected ... WebMar 2, 2024 · This guidance advocates for estimation of equivalent exposures to animal doses based on state-of-the-art pharmacokinetic or pharmacokinetic/pharmacodynamic …
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